Windows 10 is the latest and best version of the Windows operating system which was first released in 2015 and was made as a free upgrade to people who were running Windows 7 or Windows 8 on their computers. Although this is a solid performing operating system there are instances when certain issues can occur which we will be addressing today. In this latest installment of our troubleshooting series we will tackle the Windows 10 USB mouse not working\u00a0 issue. How To Fix Windows 10 USB Mouse Not Working Issue Before performing any of the recommended troubleshooting steps listed below it\u2019s best to restart your computer first. This action refreshes the operating system and remove any corrupt temporary data that could be causing the problem. There are several factors that can cause this particular issue ranging from a hardware to a system problem. Listed below are the troubleshooting steps you need to do to fix the problem. Check if the USB mouse works on other devices Sometimes this problem can be caused by a defective mouse. To make sure that the mouse is working properly you should test if it works on another computer. In case it works you should try plugging it in a different USB port in the original computer to check if it is a port related problem. Enable the USB mouse from device manager Press the\u00a0Windows key and R on the keyboardType devmgmt.msc and press Enter to open Device ManagerPress Tab to select computer name.\u00a0Use the down arrow to go to Mice and other pointing devicesPress Alt + right arrow on to go to HID-compliant mouse. If it is disabled then you will need to enable it.Press Shift + F10 or Fn + Shift + F10 to open properties list. These combination keys are simulating right click on your mouseUse the down arrow to choose Enable device and press Enter on your keyboard Check if the windows 10 USB mouse not working issue still occurs. Reinstall the mouse driver There\u2019s a possibility that the mouse driver has become corrupted and is causing the problem. If this is the culprit then you need to reinstall the driver. Press the\u00a0Windows key and press RType devmgmt.msc and press Enter to open Device ManagerPress Tab to select computer name.By using down arrow navigate to Mice and other pointing devicesPress Alt + right arrow to expand Mice and other pointing devicesBy using down arrow navigate to HID-compliant mouse.Press Shift + F10 or Fn + Shift + F10 to open properties list. These combination keys will simulate right click on your mouseBy using down arrow choose Uninstall device and press Enter on your keyboardPress Enter to confirm uninstalling mouse driverPress Alt + F4 to close mouse properties and Device ManagerHold Windows key and press RType cmd and press Enter to open Command PromptType shutdown \/r \/f \/t 0 and press Enter to restart your Windows machine Check if the windows 10 USB mouse not working issue still occurs. Change the USB Power Management settings Press the Windows+R keyType devmgmt.msc and press Enter to open Device ManagerPress Tab to select computer name.\u00a0By using down arrow navigate on Universal Serial Bus ControllersPress Alt + right arrow to expand Universal Serial Bus ControllersBy using down arrow navigate on USB Root Hub (USB 3.0). It is the USB port where USB mouse is connectedPress Enter on the keyboard to open USB Root Hub (USB 3.0) Properties.Use the Tab key to navigate to General tabBy using right arrow navigate on Power Management tabBy using Tab select Allow the computer to turn off this device to save powerPress Ctrl + Space to deselect Allow the computer to turn off this device to save powerPress EnterPress Alt + F4 to close Device ManagerHold Windows logo and press RType cmd and press Enter to open Command PromptType shutdown \/r \/f \/t 0 and press Enter to restart your Windows machine Check if the Windows 10 USB mouse not working issue still occurs. Check BIOS or UEFI settings The USB port of the computer might be disabled in the BIOS or UEFI. If this is the case then you will need to enable it. Take note that the steps listed below is a general idea of what needs to be done since each motherboard has different ways to do this. Restart the computerPress F12 to access BIOS or UEFI\u00a0Choose Devices and then choose USB SetupNavigate on USB Virtual KBC Support and choose EnabledSave BIOS configuration and restart your computer Check if the Windows 10 USB mouse not working issue still occurs.