7 Best Motherboards For AMD Radeon RX Vega 64

So you’re looking to start making your computer VR-ready, but one of the major things you need to make this happen is a high-end video card. Luckily, AMD has your back there. Enter, the Radeon RX Vega 64. This is a great video card created for demanding tasks like, well, virtual reality, gaming on “Extreme” graphics, and doing high-end video rendering in, say, 4K resolution. The card will be able to handle anything, including virtual reality processing. However, for a card like this, you do need to make sure you have the right motherboard to go with it. We’ve done all of the legwork for you by constructing this list — below you’ll find the seven best motherboards for the AMD Radeon RX Vega 64. Here are our top picks.

ProductBrandNamePrice
MSIMSI Enthusiast Gaming Intel 8th GenCheck Price on Amazon
GigabyteGIGABYTE B450M DS3HCheck Price on Amazon
ASUSASUS ROG Strix Z370-E Gaming LGA1151 (Intel 8th Gen)Check Price on Amazon
ASUSASUS Prime X470-Pro AMD Ryzen 2 MotherboardCheck Price on Amazon
ASUSASUS ROG Maximus X Hero LGA1151 (Intel 8th Gen)Check Price on Amazon

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So what do you get to go with the RX Vega 64? Your options are fairly limited, as this is a new card and won’t work with many old and existing motherboards, particularly if you’re trying to do a dual-graphics setup. But worry not — we’ve got you covered.

Best Motherboards For AMD Radeon RX Vega 64

Motherboards For AMD Radeon RX Vega 64

1. MSI Z370 Gaming M5

In number four place, we have the MSI Z370 Gaming M5 motherboard. If you’re looking for an excellent board that can support up to two Radeon RX Vega 64’s, then this board will be right up your alley. It’s an excellent mid-range motherboard; however, it does tend to run a lot hotter than some of the ROG options we have listed below. Still, it’s not a bad option for a mid-ranger. Besides, there are four DDR4 RAM slots available, supporting up to a whopping 64GB of memory for your machine. With that amount of memory, any application out there will be able to run smooth as butter.

The MSI Z370 Gaming M5 has a lot of neat appearance customization options, but beyond that, it’s a decent motherboard for overclocking as well.

Buy it now: here

 

Motherboards For AMD Radeon RX Vega 64

 

2. GIGABYTE B450M

GIGABYTE’s B450M Motherboard is an excellent choice for using with the Radeon RX Vega 64. It’s a PCIe graphics card, so it shouldn’t have a problem fitting in the board. Paired with a Ryzen processor because of the AM4 socket the board supports, you’ll be able to create a well-rounded set up for work or for gaming.

There are actually a couple of PCIe slots on the board, so you could potentially do a multi-GPU setup with this one as well.

You don’t need to pick up a dedicated audio card for the GIGABYTE B450M, either. This one comes equipped with high-end audio capacitors, as well as some other audio-related features. So, just plug in your speakers or headphones into the case, and you’re ready to roll.

Buy it now: here

 

Motherboards For AMD Radeon RX Vega 64

 

3. ASUS Prime X470

You can use the ASUS Prime X470 for a video card like the RX Vega 64. The card easily slides into the PCIe slot on the board. Since it has multiple PCIe slots, you can create a multi-GPU setup with this board, just like the last.

The motherboard supports the AM4 socket type, so you’ll be able to outfit it with a pretty sweet Ryzen processor as well. Suffice to say, you can create a pretty monster setup with this board.

The Prime X470 provides you with extra support for the RX Vega 64 by equipping its PCIe slots with SafeSlot technology. This is an injection molding process that upgrades your PCIe slots to be able to handle heavier cards and provides overall long-term durability.

It comes with several overclocking abilities as well, which is rolled into a feature they’re calling 5-Way Optimization. It’s an interface that allows you to overclock and make sure your hardware components are staying at the correct temperatures.

Buy it now: here

Motherboards For AMD Radeon RX Vega 64

4. ASUS ROG Strix Z370 E-Gaming

Our number three pick on our list is the ASUS ROG Strix Z370 E-Gaming motherboard. If you’re looking for sheer performance, then the Strix from the Republic of Gamers line will be right up your alley. There’s nothing “cheap” about the Republic of Gamers line of hardware products — each product is meant to be used in high-end applications, and that goes for the Strix as well. Suffice to say, it’ll have no trouble working with even a dual-card setup, such as two Vega 64’s. The Strix actually has some unique technology built into it — ASUS’ own proprietary FanXpert 4 system, which tailors your overclocking profile to meet your individual demands and puts you in control of just how hard you can push your computer, or more specifically, your video card.

Buy it now: here

Motherboards For AMD Radeon RX Vega 64

5. ASUS ROG Maximus X Hero

Coming in at number one place, we have the Maximus X Hero by the ASUS Republic of Gamers. If you’re a serious gamer or professional, then the Maximus X Hero will be right up your alley. Built for power and performance right out of the box, the Maximus X Hero was designed to push your hardware to their limits. There’s a variety of overclocking abilities on-board, and it even comes with the same FanXpert proprietary technology found in the Strix. You’re able to maximize overclocking performance and keep your machine running cool simultaneously. Even when you’re pushing your video cards to their limits. ASUS also knows that you want to keep your motherboard looking sick — that said, using the Asus Aura Sync, you can trick out your motherboard with some neat RGB lighting.

Buy it now: here

Motherboards For AMD Radeon RX Vega 64

6. ASRock Z370 EXTREME 4

The ASRock Z370 EXTREME 4 is an excellent choice for your Vega 64 — you might not be able to fit two cards on this system, but it’ll handle one just fine. Of course, this motherboard will work with any modern processor as well, so that you can genuinely get maximum power. There’s an excellent IO on this motherboard, and there are a whole four DDR4 RAM slots available. That means you can outfit this motherboard with up to 64GB of memory if you so choose.

Buy it now: here

Motherboards For AMD Radeon RX Vega 64

7. GIGABYTE Z370 AORUS Gaming 7

And coming in second place is GIGABYTE’s very own Z370 Aorus Gaming 7 motherboard. If you need something that can keep pace with up to two RX Vega 64’s, it’s the Aorus Gaming 7. Not only will it be able to handle the power output of the video cards, but it comes with several built-in video card overclocking options for getting the most out of your graphics cards. The Aorus Gaming 7 even supports GIGABYTE’s Triple M.2 Support technology that dissipates heat from the board before it causes problems. There are even nine temperature sensors spread across the Gaming 7 to sense cooling issues and keep you running at peak performance, also when you’re pushing your video card(s) to their limits.

Buy it now: here

Best Motherboards For AMD Radeon RX Vega 64 Verdict

There are a lot of great motherboards available for the AMD Radeon RX Vega 64. Whether you’re trying to build or upgrade a PC for VR, high-end gaming, or do some professional or hobby work, there’s a motherboard for you on this list to go with your Vega 64. However, if you use your PC on a daily basis and are constantly pushing your equipment — invest in something long-term like the Maximus X Hero. Do you have a favorite motherboard for the RX Vega 64? Let us know what it is in the comments section below!

ProductBrandNamePrice
MSIMSI Enthusiast Gaming Intel 8th GenCheck Price on Amazon
GigabyteGIGABYTE B450M DS3HCheck Price on Amazon
ASUSASUS ROG Strix Z370-E Gaming LGA1151 (Intel 8th Gen)Check Price on Amazon
ASUSASUS Prime X470-Pro AMD Ryzen 2 MotherboardCheck Price on Amazon
ASUSASUS ROG Maximus X Hero LGA1151 (Intel 8th Gen)Check Price on Amazon

* If you buy through links on our site, we may earn an affiliate commission. For more details, please visit our Privacy policy page.